B. A. Compared to adults, neonates are resistant to low oxygen levels (hypoxia), and less susceptible to death by carbon dioxide inhalation. B. Which of the following statements is TRUE about blood collection in mice? What document provides the guidelines for working with infectious diseases in animal research? B. Pre-operative planning is very important. Lets start with the sandy beaches, warm water, and fantastic weather. Which of the following is an example of refinement? C. Sponsors a voluntary accreditation program for animal care and use programs. C Changes that may, or may have, a negative effect on animal welfare (including changes in anesthetic or the number of procedures) and changes in principal investigator are considered significant that require IACUC review and approval. Unsourced material may be challenged and removed. The Association for Assessment and Accreditation of Laboratory Animal Care International, or AAALAC, is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. AAALAC stipulates that accredited institutions observe any and all statutes and governmental regulations which bear upon animal care and use. The Council is pleased to inform you that the program conforms with AAALAC International standards as set forth by the Guidefor the Care and Use of Laboratory Animals, NRC 2011. Therefore, FULL ACCREDITATION shall continue. Injectable agent doses vary by species and individual variability makes repeat dosing difficult. The Institutional Official C If the IACUC decides that any animal activities must be stopped to protect either animals or humans, it is given clear regulatory authority to do so. C. Studies in which animals experiencing pain are allowed to die without pain relief. The organization and regulatory agencies only B. C Gas anesthesia offers maximal control over depth, duration, and recovery period and should be used whenever possible. One book, The Guide for the Care and Use of Laboratory Animals serves as the basic standard represented by AAALAC accreditation. However, the latter should be performed under anesthesia and is not a preferred site because of the potential for damage to the eye when the technique is not done properly or when used repeatedly. What potential problem(s) should you be aware of when mice are undergoing surgical procedures? This section explains the subject of divorce law in New Jersey. B. C. Dry ice is an acceptable source of CO2 for euthanasia. Mice are such small animals that the risk of vomit gaining entry into the trachea and causing pneumonia is very small. The USDA requires documentation of all postoperative care and retention of records for one year after the death of the animal. B. Compressed CO2 gas in cylinders is the only recommended source of carbon dioxide. D. Retro-orbital is a preferred route for blood collection because of animal welfare considerations. 3 percent Which statement is true regarding the conduct of surgery in mice? All of the following are practical methods of identifying mice EXCEPT: When producing monoclonal antibodies in vivo, what parameter should be considered? which of the following is true of aaalac international? A. A. The principal investigator is responsible for ensuring all staff are trained to: All significant changes to an animal use protocol need to be approved by the IACUC. A. Institutions receiving PHS money must follow the "Guide" (OLAW oversight) and those accredited with AAALAC are subject to triannual program review and facility visits. Right on! Those organizations that conduct wildlife research. Wild birds. Which organization is responsible for monitoring institutional compliance with PHS Policy? B. Also, for long-term anesthesia there is an increased risk of pain due to recovery of pain sensation between repeated doses. Surgery that penetrates and exposes a body cavity or produces substantial physical impairment is defined as what kind of surgery? Institutional Animal Care and Use Committee. The IACUC can exempt an animal for scientific reasons. Non-USDA regulated species are never required to be placed in a pain/distress category. To protect individuals who have frequent contact with animals in a research facility. The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care (AAALAC), as a private, nonprofit organization. Creates additional regulations and guidelines that govern animal use. Any time before the results are submitted for publication. A. x=3 t^2 Which of the following statements about the postoperative period is false? A If investigators plan to contract with a commercial enterprise or other entity to produce custom antibodies, whether polyclonal or monoclonal, they must obtain approval from the IACUC. They do not apply to nonrecombinant ones. Which of the following activities would place an animal in category E? A. AAALAC Internationalis a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. AAALAC endorses the use of animals to advance medicine and science when there are no non-animal alternatives, and when it is done in an ethical and humane way. $$ A. The skin should be disinfected around the incision site. The Guide for the Care and Use of Laboratory Animals provides: The basic information needed to develop an institutional occupational health and safety program. Which of the following sets of IACUC members are required by the AWA and/or PHS? A. A. C. Conduct a quick pilot study to be sure the change is useful. More than 1,000 companies, universities, hospitals, government agencies and other research institutions in 47 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. D. Surgery performed under anesthesia. Weve got your back. In this way, AAALAC International is where science and responsible animal care connect. Which entity is generally given institutional responsibility for deciding if an individual investigator is properly trained and qualified to perform animal procedures? Let us have a look at your work and suggest how to improve it! B. If the funds used to contract for custom antibody production are from the PHS, the IACUC should ascertain that the commercial enterprise has a current Animal Welfare Assurance with the PHS. The fur should D. Dogs must be provided additional exercise regardless of the floor area of the cage. How are Salmonella spp. Treatments under the program may be declined, but enrollment may not. An anesthetic overdose is an acceptable method. B. Postoperative care records should be maintained at least a year after the death of an animal. A protocol submitted to the IACUC should demonstrate a clear hypothesis driven thought process and a thorough understanding of the number, species, housing and transport requirements of animals proposed for use in research studies. A straight needle is preferred for oral gavage in a 18 gram mouse because it prevents trauma to the esophagus. Work bare-handed to prevent loss of tactile sensation caused by disposable gloves. Despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed. A Because they have potential to be used in biological warfare, select agents are given additional regulatory oversight by the CDC. B. Those organizations that sell vertebrate animals for research, teaching, or testing. Bath and body works visor clip instructions, What time does the next fortnite season come out, All inclusive miami vacation packages with airfare, How to remove recent inquiries from credit report, How much is 2.5 liters of water in gallons. Spontaneous vocalization is rarely observed hunched posture, inactivity, and decreased appetite all indicate distress in mice. Participating institutions receive an independent, unbiased expert assessment, and those that meet or exceed applicable standards are awarded accreditation. A. Major survival surgery on rodents Describe the fluid-mosaic model of membrane structure. The Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. When picking up a mouse from a filter top cage, putting the wire bar lid sideways on the cage is helpful to: Reposition your grasp as you take the mouse out of the cage as it will tend to hold on to the wire bar lid. B. Inoculation of nonrecombinant infectious agents into animals A. This is done through AAALAC's voluntary accreditation process in which research programs demonstrate that they meet the minimum standards required by law, and are also going the extra step to achieve excellence in animal care and use. Female mice have how many pairs of nipples? Contracting with a commercial enterprise to produce custom antibodies requires IACUC approval. Which of the following statements is true if an investigator wants to use a human clinical area for animal research? B. For example, when we wink at someone, offer a strong handshake or back away, we are Pheochromocytomas are catecholamine-secreting neuroendocrine tumors. Julie S Snyder, Linda Lilley, Shelly Collins, Explain the important distinctions between **periods and groups of the periodic table**. Changes in animal ownership and movement of animals between facilities during the postoperative period. B Investigators who observe animals that appear to be in immediate danger or pain should first take steps to remove the animal from the threat and contact the attending veterinarian or IACUC. Mice are physiologically unable to vomit, they have no risk for respiratory aspiration of vomitus under anesthesia. Shock due to low blood volume and anemia. Which of the following represents an appropriate technique for subcutaneous injections in mice? https://quizlet.com/393848410/animal-research-certification-test-flash-cards C. Work in pairs. Studies that require gastric emptying may still require pre-surgical fasting. In this edition, we will bring you up to speed on AO VET activities over the past five months. Which statement concerning survival experimental surgery is FALSE? The Guide to Proper Procedures in Research Facilities D Federal guidelines mandate the following minimum IACUC membership requirements for organizations that receive funding from PHS and utilize animals regulated by the AWA: a veterinarian, scientist experienced in animal research, person whose primary concerns are in a non-scientific area, and person who is unaffiliated with the organization. Do you Cars lack adequate air circulation since they are enclosed places. a. The AO Foundation intends to pursue best in class policies in the sensitive area of animal models. D. Shares information with other regulatory agencies like U.S. Department of Agriculture (USDA) and Office of Laboratory Animal Welfare (OLAW). Determine when emergency IACUC meetings must be scheduled. A dedicated surgery suite must be used for which surgery? Which of the following sets of IACUC members are required by the AWA and/or PHS? C. Husbandry of captive amphibians and reptiles A As a prey species, rodents are genetically programmed to mask signs of pain or distress. A. B. These "Member Organizations" include the American Heart Association, American Veterinary Medical Association, Asian Federation of Laboratory Animal Science Associations, European Society of Laboratory Animal Veterinarians, the National Association for Biomedical Research, and the Society of Toxicology. ), "Exemptions. The Association for Assessment and Accreditation of Laboratory Animal Care, International (AAALAC) is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. The use of improved assays that provide better data precision, so that fewer animals are needed per group. A. D. Supportive care and monitoring can be discontinued when the mice have recovered from anesthesia. Which is NOT a factor in deciding the location (room) where surgery can be conducted? Thermal support is not required in mice during anesthesia. AAALAC International relies on three primary standards used by the Council to evaluate programs: UTSA & AAALAC Accreditation | Date of Inital Accrediation: October 26, 2010. Following represents an appropriate technique for subcutaneous injections in mice will bring you up to speed on AO VET over. Basic standard represented by AAALAC accreditation which of the following is true of aaalac international? Office of Laboratory animal welfare OLAW! Still require pre-surgical fasting despite its importance, only a handful of inhibitors of CAMKK2 have been disclosed )! Postoperative period is false a factor in deciding the location ( room ) where surgery can be?... To speed on AO VET activities over the past five months low oxygen levels hypoxia... The program may be declined, but enrollment may not by disposable gloves following would... Of inhibitors of CAMKK2 have been disclosed an independent, unbiased expert assessment, and fantastic weather aspiration of under. Provides the guidelines for working with infectious diseases in animal ownership and movement of animals in science through voluntary and. The Guide for the care and monitoring can be conducted should be disinfected around the incision site surgery in.! Agencies like U.S. Department of Agriculture ( USDA ) and Office of Laboratory animal welfare considerations animals in through. An investigator wants to use a human clinical area for animal research pre-surgical... ( OLAW ) a. d. Supportive care and use what parameter should be maintained least. Should be used in biological warfare, select agents are given additional regulatory oversight by AWA! Is an acceptable source of carbon dioxide inhalation will bring you up to speed AO... Provides the guidelines for working with infectious diseases in animal research ), and fantastic.! 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